New Advances in the development of diagnostic and therapeutic approaches in health and disease

26-27 August 2021, Fr. R. Kreutzwaldi 1a, Tartu, ESTONIA

About The Event


We are pleased to invite you to a two-day symposium about EXTRACELLULAR VESICLES IN PATHOPHYSIOLOGY | New advances in the development of diagnostic and therapeutic approaches in health and disease that will take place on August 26-27, 2021 as and hybrid event – in a VIRTUAL room and at the Estonian University of Life Sciences (Eesti Maaülikool)


Estonian University of Life Sciences, Fr. R. Kreutzwaldi 1a, Tartu, ESTONIA


Thursday to Friday
26-27 August 2021

About the Event

The first symposium of the COMBIVET ERA Chair of Comparative Medicine in the Institute of Veterinary Medicine and Animal Sciences of the Estonian University of Life Sciences is aimed to gather lecturers and experts from different EV related research fields. The presentations are aimed at illustrating different methods of cell-cell communication and its effects on cellular function as well as the role that they can play in the diagnosis and therapies of patients.  Furthermore, the applications of volatiles in EV Research, and the potential of using agri-food wastes and by-products as a cost-effective source for mass production of EVs as a natural additive in food, cosmeceuticals and/or in pharmaceutical applications will be discussed. 
     COMBIVET ERA Chair has set an objective to host symposiums to bring prominent experts in the field to exchange the most recent knowledge in this growing field and advance research cooperation with the Estonian University of Life Sciences (Eesti Maaülikool).
      The symposium will feature the following sessions:

  • EVs in Physiology and Pathology
  • Extracellular vesicle methodologies and VOCs
  • Valorization of food waste and plant EVs

Considering the possible travel restrictions, we are organizing the event as a hybrid event. Therefore, those who cannot attend in person can take part in the event using the virtual platform.

Event Speakers

EVs in Physiology and Pathology- I.


Opening Words

Morning Session

Stefano Pluchino

Targeting Mitochondrial Metabolism in Neuroinflammation with Neural Stem Cells and their Cargo Vesicles.

Martjin van Herwinjen

Mother’s utilise milk-derived extracellular vesicles for supporting her developing infant.

Pieter Vader

Extracellular vesicle-mediated RNA delivery: from mechanistic insights to therapeutic applications

Coffee break

Juliano C. da Silveira

The Role of Small Extracellular Vesicles In The Ovarian Follicle.

Dawit Tesfaye

The Role of Extracellular Vesicles in Mitigating the Effect of Heat Stress.

EV methodologies and application of Volatile Organic Compounds in EV research


Afternoon Session

Bernd Giebel

Mesenchymal Stem Cell-Derived Extracellular Vesicles: Potential Modulators of the Immune System in Many Diseases

Edwin van der Pol

The dos and don’ts of single extracellular vesicle detection.

Sergei Kopantšuk

Fluorescence anisotropy and TIRF microscopy: from viruses to exosomes and from GPCRs to tetraspanins.

Coffee break

Hossam Haick

Volatile Compounds Are Involved in Cellular Crosstalk and Upregulation

Aylen Lisset Jaimes-Mogollón


Gala Dinner

EVs in Physiology and Pathology -II


Morning Session

Dimitrios Rizos

Extracellular Vesicles and embryo-maternal communication during preimplantation development in cattle

Masaharu Somiya

Development of quantitative bioassays to study cargo delivery mechanism and efficiency of extracellular vesicles

Anindya Mukhopadhya

Milking Extracellular Vesicles: Separation and Characterisation of Milk EVs and their further applications

Coffee break

Pia R-M Siljander

EV heterogeneity

Nadezhda Nikiforova

New method for increasing detection sensitivity of cancer derived Extracellular Vesicles: semi-quantitative analysis using "on-bead" flow cytometry.

Valorization of food waste and plant EVs


Afternoon Session

Rajeev Bhat

A novel approach for valorization of fruits and vegetable wastes/by-products: Exploring the opportunities for mass production of plant-based extracellular vesicles (EVs):

Carine de Marcos

Plant EVs as therapeutic drug delivery systems

Alfredo Ambrosone

Plant Nano and microvesicles: Biological Role and Potential Applications for Plant protection and Human Health .

Coffee break

Roger Innes

Extracellular RNA in Plants: Where Does It Come From and What Does It Do?

Closing Words

Event Venue

Event venue location info and gallery

Estonian University of Life Sciences, Fr. R. Kreutzwaldi 1a, Tartu


Participation is free of charge, although registration is required.
Registration deadline extended to: August 25th, 2021 To register, please add your details below:
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